Bisquick Impossible Pizza Pie

Category: Dinner Ideas That Actually Work

This Bisquick Impossible Pizza Pie brings together rich seasoned ground beef, sautéed onions, pepperoni, and marinara sauce in tasty layers. The addition of Bisquick, eggs, and milk forms a tender, slightly crisp crust above and below the beef and melted mozzarella cheese. Baked until golden and bubbly, this dish is ideal for anyone craving the flavors of pizza without traditional dough. It's simple to prepare in just over 30 minutes and makes a comforting hot dinner. Custom toppings such as extra pepperoni or different cheeses can be added before baking for even more flavor.

Lili Clark smiling at the camera.
Created By Lili Clark
Updated on Thu, 19 Feb 2026 17:13:40 GMT
A slice of Bisquick Impossible Pizza Pie. Save
A slice of Bisquick Impossible Pizza Pie. | lilicooks.com

Weeknight dinners need to be quick but still feel special and comforting This Bisquick Impossible Pizza Pie does exactly that Pizza flavors everyone loves with almost no shaping dough to fuss over Savory beef gooey cheese and a golden topping all in one pan make it almost too easy and it is a crowd pleaser every single time it hits the table

I whipped this up on a night when delivery was an hour wait and now my spouse actually requests it over takeout Pizza night has gotten so much easier

Ingredients

  • Ground beef: Choose an 80 to 85 percent lean blend for best flavor without being greasy
  • Diced onion: Adds natural sweetness and balances the savoriness If using sweet onions or yellow onions either works
  • Salt and pepper: Brings out flavors Taste your beef so you do not underseason
  • Paprika Italian seasoning Onion powder: Create that signature pizza shop flavor Smoked paprika adds an extra touch if you like
  • Crushed red pepper flakes: Gives a gentle heat adjust for your family
  • Minced garlic: Fresh or jarred both work just make sure the garlic is fragrant for maximum flavor
  • Marinara sauce: A tomato base is essential Use a brand you love or homemade for fresh taste
  • Chopped pepperoni: Real pizza bite comes from these Try for the small cupandchar kind if possible
  • Bisquick: This is what makes it "impossible" and gives structure Stick with the classic mix for consistent results
  • Eggs: Bind the topping for a custardy finish Local or free range eggs give a rich flavor
  • Milk: Full fat or twopercent works best for a tender crust
  • Shredded mozzarella cheese: Buy a block and shred for meltier texture prebagged sometimes has extra starch
  • Extra pepperoni for topping: Makes it look and taste like true pizza

Step-by-Step Instructions

Brown the Beef and Onion:
Cook the ground beef and diced onion over medium heat until meat is browned and onions are translucent This usually takes about 67 minutes Take your time so the onion softens well and the beef develops a full flavor
Season the Beef:
Sprinkle in the salt pepper paprika Italian seasoning onion powder and crushed red pepper flakes Stir thoroughly so all the beef is well coated with spice Let this cook 1 more minute This step is your major flavor boost
Cook Pepperoni and Drain:
Toss chopped pepperoni into the skillet with the beef Let it cook 23 minutes so the pepperoni releases its oil and aroma Flavor will deepen now Drain away excess grease very well so the pie does not end up oily
Add Marinara and Garlic:
Pour in the marinara sauce and minced garlic Stir everything together until fully combined Remove the pan from heat so nothing scorches or overcooks at this point
Prep the Bisquick Topping:
In a separate bowl whisk the Bisquick eggs and milk smoothly together No lumps You want a batter the consistency of pancake mix This is your magic top layer
Assemble the Pie:
Spray your pie pan generously with cooking spray No sticking here Layer half the beef mixture evenly on the bottom Sprinkle over one cup of shredded mozzarella Top with the rest of the beef and another cup of cheese Do not press down Just layer gently
Add Bisquick Mixture and Decorate:
Pour the Bisquick batter evenly all over the beef and cheese making sure it coats everything Top with additional slices of pepperoni to taste
Bake to Golden Finish:
Put the pie into a preheated 400 degree oven Bake for about 25 minutes The top will turn deep golden and a tester should come out clean from the center Let rest 5 minutes before slicing for neat pieces
A slice of Bisquick Impossible Pizza Pie. Save
A slice of Bisquick Impossible Pizza Pie. | lilicooks.com

My favorite part is always the crispy edges around the pan where the cheesy Bisquick topping meets the pepperoni Growing up my mom used to make the "impossible pies" and I finally dared try my own spin Now this is the most requested dish at our family meetups I love how the kitchen always smells like pizza parlor

Storage tips

Let leftovers cool to room temperature then cover and store in the fridge for up to four days To freeze wrap slices individually so you can grabandgo For reheating use the oven or toaster oven to restore crispness The microwave works but the topping will be softer

Ingredient substitutions

If you want a lighter version swap in ground turkey or even crumbled cooked sausage Veggie lovers can use plantbased grounds or finely diced mushrooms for a hearty meatfree option You can also stir in bell peppers or olives with the beef Pepperjack cheese or cheddar make bold flavor swaps if you are out of mozzarella

A slice of Bisquick Impossible Pizza Pie. Save
A slice of Bisquick Impossible Pizza Pie. | lilicooks.com

Serving suggestions

Serve this with a quick green salad or roasted broccoli on the side A sprinkle of fresh basil at the end is a vibrant touch In our house it is a party food too Sometimes I slice it into squares for a buffet spread at game nights

Cultural and historical context

The Impossible Pie idea came from Bisquick’s recipe box in the 1970s A clever hack to avoid pie crust this method swept home kitchens across America Thanks to the layered flavors and nostalgic factor it is become a new classic with endless possibilities

Recipe FAQs

→ Can I use turkey instead of ground beef?

Yes, ground turkey can replace ground beef for a lighter, leaner option. Adjust seasoning to taste for added flavor.

→ What can I substitute for Bisquick?

You can use other all-purpose baking mixes or create a quick substitute with flour, baking powder, salt, and a bit of softened butter.

→ Do I need to pre-cook the pepperoni?

The sliced pepperoni is added to the cooked beef mixture and also as a topping, so it will heat and crisp up during baking.

→ Can this be made ahead of time?

Yes, assemble the dish and refrigerate before baking, or bake ahead and reheat individual slices when ready to serve.

→ Is this dish gluten-free friendly?

Use a gluten-free baking mix in place of Bisquick and verify all other ingredients are certified gluten-free.

→ What cheese works best for this dish?

Mozzarella provides classic melting texture, but cheddar or a mozzarella-cheddar blend can add richer flavor.

Bisquick Impossible Pizza Pie

Savor layers of seasoned beef, pepperoni, and cheese with a light Bisquick crust for a quick dinner favorite.

Preparation Time
10 min
Cooking Time
25 min
Overall Time
35 min
Created By: Lili Clark

Category: Dinner

Skill Level: Beginner-Friendly

Cuisine Type: American

Output: 1 pie

Dietary Options: ~

Ingredients

→ Meat and Protein

01 1 lb ground beef
02 1/4 cup chopped pepperoni + additional for topping

→ Vegetables

03 1 diced onion

→ Seasoning

04 1/2 tsp salt
05 1/2 tsp black pepper
06 1 tsp paprika
07 1 tsp Italian seasoning
08 1 tsp onion powder
09 1/4 tsp crushed red pepper flakes
10 1 TBSP minced garlic

→ Sauce

11 1 cup marinara sauce

→ Batter

12 1/2 cup Bisquick
13 2 eggs
14 3/4 cup milk

→ Cheese

15 2 cups shredded mozzarella cheese

Steps

Step 01

Brown the ground beef with the diced onion in a skillet over medium heat. Add the salt, pepper, paprika, Italian seasoning, onion powder, and crushed red pepper flakes. Cook until the beef is fully browned.

Step 02

Once the beef is browned, add the chopped pepperoni and cook for a few minutes. Drain excess grease from the skillet. Add the marinara sauce and minced garlic, stir well, and remove the skillet from heat.

Step 03

In a bowl, whisk together the Bisquick, milk, and eggs until smooth.

Step 04

Spray a pie pan with cooking spray. Layer half of the ground beef mixture in the pie pan, followed by 1 cup of shredded mozzarella. Add the remaining beef mixture and top with another cup of mozzarella. Pour the Bisquick batter evenly over the top and garnish with additional pepperoni.

Step 05

Bake in a preheated oven at 400°F (200°C) for 25 minutes or until golden brown and set.

Required Tools

  • Skillet
  • Whisk
  • Mixing bowl
  • Pie pan
  • Cooking spray

Allergy Information

Always check each ingredient for allergens, and consult a medical professional if unsure.
  • Contains dairy (cheese, milk)
  • Contains gluten (Bisquick)
  • Contains eggs

Nutritional Information (per serving)

These details are shared for general guidance and don’t replace professional advice.
  • Calories: 380.5
  • Fats: 28.1 g
  • Carbohydrates: 15.2 g
  • Proteins: 18.5 g