Cajun Salmon and Shrimp Bake

Category: Dinner Ideas That Actually Work

This dish combines tender salmon fillets and juicy shrimp baked together with a rich, buttery Cajun seasoning. Garlic, smoked paprika, and thyme blend to create a smoky, slightly spicy flavor that fills the kitchen as it cooks. Nestled alongside sliced onions and finished with fresh parsley and lemon, the seafood stays moist and flaky thanks to the butter and olive oil. Baking at 400°F ensures a perfect flaky texture, with an optional quick broil for a crisp finish. A simple, flavorful one-pan meal that’s bright and satisfying.

Labels: #high-protein #gluten-free #low-carb

Lili Clark smiling at the camera.
Created By Lili Clark
Updated on Wed, 18 Mar 2026 23:58:53 GMT
A pan of Cajun Salmon and Shrimp Bake. Save
A pan of Cajun Salmon and Shrimp Bake. | lilicooks.com

Some nights call for something bold. Something with a little heat, a little brightness, and a whole lot of flavor. This Cajun Salmon and Shrimp Bake brings all that to your table with tender, flaky salmon and juicy shrimp coated in a buttery, garlicky Cajun seasoning. It’s a one-pan meal that feels special without taking hours to prepare. The lemon juice squeezed on top at the end adds a fresh, vibrant finish that makes every bite memorable.

This dish always surprises me with how quickly it comes together yet delivers a big, satisfying flavor punch. I first made it for a casual weeknight dinner and now it’s a go-to whenever I want something easy but impressive.

Ingredients

  • Four salmon fillets about six ounces each: look for firm, fresh fillets with a bright color
  • One pound large shrimp peeled and deveined: choose shrimp that smell fresh and not overly fishy
  • Two tablespoons olive oil: helps carry the spices and keeps everything moist
  • Two tablespoons unsalted butter melted: adds richness and a silky texture
  • Three cloves garlic minced: garlic adds warmth and depth
  • One tablespoon Cajun seasoning: the star spice blend that delivers heat and complexity
  • One teaspoon smoked paprika: brings a smoky undertone, especially if you can find Spanish smoked paprika
  • Half teaspoon dried thyme: balances the spice with an herbal note
  • Half teaspoon salt: adjust based on your preference
  • Half teaspoon black pepper: fresh cracked for the best aroma
  • One medium onion sliced into wedges: cooks down to sweetness and softness
  • One tablespoon fresh lemon juice: brightens the dish and cuts through the richness
  • One tablespoon fresh parsley chopped for garnish: adds color and a fresh herbal touch
  • Lemon wedges for serving: for squeezing on top to add zing

Step-by-Step Instructions

Preheat the Oven:
Set your oven to 400 degrees Fahrenheit or 200 degrees Celsius. Lightly grease a baking dish or line it with foil for easier cleanup. Preheating ensures even cooking when you add the seafood.
Make the Seasoning Mixture:
In a small bowl, stir together olive oil, melted butter, minced garlic, Cajun seasoning, smoked paprika, thyme, salt, pepper, and lemon juice. Mixing thoroughly helps the flavors marry and the aroma becomes rich, smoky, and slightly spicy.
Arrange the Seafood:
Place salmon fillets in the center of the baking dish. Tuck shrimp and onion wedges around the salmon. It does not have to be perfect; rustic is the charm here and helps everything cook evenly.
Coat Everything Generously:
Use a brush or spoon to coat the salmon and shrimp with the seasoning mixture. Make sure every piece has a glossy, flavorful layer. The fats keep the seafood moist while the spices build layers of flavor.
Bake:
Place the baking dish in the oven and bake for 15 to 18 minutes. Salmon will flake easily with a fork indicating it is done. Shrimp will turn pink and opaque. Watch closely to avoid overcooking, which can make seafood tough.
Optional Broil for Crispness:
If you prefer a slight crisp on top, switch to broil for one to two minutes at the end, watching very carefully to prevent burning. This step adds a lovely texture contrast.
Garnish and Serve:
Remove from the oven and sprinkle chopped fresh parsley on top. Serve immediately with lemon wedges for squeezing. The lemon juice adds that perfect citrus brightness, making every bite sing.
A dish of Cajun Salmon and Shrimp Bake.
A dish of Cajun Salmon and Shrimp Bake. | lilicooks.com

My favorite ingredient here is smoked paprika. It ties the spices together with its subtle smokiness, making the dish feel rich without heaviness. One family dinner stands out when my kids asked for lemon wedges and proudly squeezed extra juice, making the whole meal even tastier.

Storage Tips

Cool leftover seafood completely before storing it in an airtight container. Keep it in the refrigerator for up to two days. Reheating gently in the oven or on the stove prevents the salmon and shrimp from drying out. This bake tastes best fresh but still holds up well if stored properly.

Ingredient Substitutions

If you do not have fresh shrimp, frozen works fine just thaw fully and pat dry. You can swap smoked paprika for regular paprika if necessary but the smoky flavor is a key part of the dish. Fresh lemon juice is best but bottled lemon juice is acceptable in a pinch.

Serving Suggestions

This bake pairs wonderfully with a simple green salad or steamed rice to soak up the buttery Cajun sauce. Crusty bread is perfect for mopping up every last bit if you want something heartier.

Recipe FAQs

→ What type of seafood is best for this dish?

Fresh salmon fillets and large peeled, deveined shrimp work best for tender, juicy results.

→ How do the Cajun spices affect the flavor?

The Cajun seasoning blends smoky paprika, garlic, and herbs, adding a bold, slightly spicy kick that complements the seafood beautifully.

→ Can I prepare this dish ahead of time?

Yes, you can assemble the seafood and seasoning mixture before baking, then refrigerate briefly until ready to cook.

→ Is there a way to get a crispier top on the seafood?

Switch the oven to broil for 1-2 minutes at the end of baking to add a slight crisp without overcooking.

→ What sides pair well with this dish?

Light salads, roasted vegetables, or steamed rice complement the bold flavors and keep the meal balanced.

→ How can I adjust the seasoning for milder taste?

Reducing the Cajun seasoning slightly or omitting the smoked paprika can soften the spice and smoky notes.

Cajun Salmon Shrimp Bake

Tender salmon and shrimp coated in buttery, garlicky Cajun spices baked with lemon and fresh herbs.

Preparation Time
15 min
Cooking Time
18 min
Overall Time
33 min
Created By: Lili Clark

Category: Dinner

Skill Level: Moderate

Cuisine Type: Cajun

Output: 4 Serves (4 salmon fillets with shrimp)

Dietary Options: Low-Carb, Gluten-Free

Ingredients

→ Seafood

01 4 salmon fillets (6 oz each)
02 1 lb large shrimp, peeled and deveined

→ Seasoning and Flavoring

03 2 tbsp olive oil
04 2 tbsp unsalted butter, melted
05 3 cloves garlic, minced
06 1 tbsp Cajun seasoning
07 1 tsp smoked paprika
08 ½ tsp dried thyme
09 ½ tsp salt, adjust to taste
10 ½ tsp black pepper
11 1 tbsp fresh lemon juice

→ Produce

12 1 medium onion, cut into wedges
13 1 tbsp fresh parsley, chopped (for garnish)
14 Lemon wedges (for serving)

Steps

Step 01

Preheat oven to 400°F (200°C). Lightly grease a baking dish or line it with foil for easy cleanup.

Step 02

Combine olive oil, melted butter, minced garlic, Cajun seasoning, smoked paprika, dried thyme, salt, black pepper, and lemon juice in a small bowl. Stir until fully blended.

Step 03

Place salmon fillets in the center of the prepared baking dish. Nestle shrimp and onion wedges evenly around the salmon.

Step 04

Brush or spoon the seasoning mixture evenly over the salmon, shrimp, and onions, ensuring all pieces are well coated.

Step 05

Bake in the preheated oven for 15 to 18 minutes, until salmon flakes easily and shrimp turn pink and opaque. Monitor closely to prevent overcooking.

Step 06

For a crispier top, broil on high for 1 to 2 minutes. Watch carefully to avoid burning.

Step 07

Remove from oven, sprinkle with fresh parsley, and serve immediately with lemon wedges.

Tips

  1. Use fresh lemon juice to enhance the brightness of the dish; adjusting salt allows control over seasoning balance.

Required Tools

  • Oven
  • Baking dish
  • Small mixing bowl
  • Brush or spoon for seasoning application

Allergy Information

Always check each ingredient for allergens, and consult a medical professional if unsure.
  • Contains seafood and shellfish allergens
  • Contains dairy (butter)

Nutritional Information (per serving)

These details are shared for general guidance and don’t replace professional advice.
  • Calories: 420
  • Fats: 25 g
  • Carbohydrates: 6 g
  • Proteins: 40 g