Bubble Up Pizza Bake

Category: Recipes That Started My Cooking Journey

This bubbly pizza casserole brings together buttery biscuit pieces, savory Italian sausage, melty mozzarella, and crisp pepperoni for a crowd-pleasing dinner. Simply toss biscuit chunks with parmesan, garlic, and Italian seasonings, and bake until golden. Top with pizza sauce, sausage, cheese, and pepperoni, then bake again until the cheese melts and the pepperoni turns crispy. The result is a warm, gooey dish perfect for a casual family meal or a quick lunch. Feel free to add your favorite pizza toppings and enjoy this comfort classic hot out of the oven.

Labels: #kid-friendly

Lili Clark smiling at the camera.
Created By Lili Clark
Updated on Wed, 22 Apr 2026 18:56:51 GMT
A plate of bubble up pizza bake. Save
A plate of bubble up pizza bake. | lilicooks.com

Bubble Up Pizza Bake is the ultimate nostalgic comfort food that comes together fast and guarantees smiles from the whole table. If you are craving classic pizza flavors but want something extra fun and simple, this bubbly casserole brimming with cheesy layers and biscuits will be your new favorite weeknight dinner.

The first time I made this my kitchen smelled just like my childhood pizza parlor and my family could not wait for it to cool enough to dive in. Now it is our go to on busy school nights when everyone wants pizza but we need something hearty and simple.

Ingredients

  • Canned biscuits: this is the secret to making it so quick and pillowy choose homestyle for a fluffy texture always check for freshness for the best rise
  • Salted butter: brings richness and helps the seasonings stick to the biscuits use real butter when you can
  • Fresh garlic: for real punch nothing beats a generous handful of minced cloves go for firm bulbs with tight skins
  • Dried oregano or Italian seasoning: classic pizza flavor in every bite look for a vibrant color and strong fragrance
  • Dried parsley: brightens up the whole casserole select jars that are vivid green
  • Grated parmesan cheese: nutty and savory helps create that golden topping always grate your own for maximum flavor
  • Pizza sauce: gives that classic zingy tomato base choose your favorite jarred variety or make your own if you want extra pizzazz
  • Italian sausage: hearty protein and tons of flavor go for quality bulk sausage and brown well for depth
  • Grated mozzarella: classic meltiness and stretch use whole milk mozzarella for richer results
  • Pepperoni slices: salty spicy and a bit crispy when baked look for uniform slices that are slightly glossy
  • Your favorite pizza toppings: peppers olives onions whatever you love these add color and flavor

Step-by-Step Instructions

Prep the Oven:
Preheat your oven to 400 degrees so it is hot and ready when you assemble everything. A properly heated oven ensures the biscuits puff up perfectly.
Chop the Biscuits:
Cut each canned biscuit into nine even pieces to create little dough pillows. This makes every bite fluffy and ensures the toppings fill every gap.
Make the Garlic Butter Mixture:
Melt the butter in a bowl until fully liquid then stir in the minced garlic dried oregano dried parsley and grated parmesan. Toss the biscuit pieces in this mix until each one is completely coated. This is the step that gives every bite tons of flavor and those dreamy golden edges.
Layer and Bake the Biscuits:
Transfer the coated biscuit pieces into a 9 by 13 baking dish spreading them evenly. Bake for twelve to fifteen minutes until the top starts to turn golden and the biscuits are almost cooked through but not dry.
Cook the Toppings:
While the biscuits bake cook the Italian sausage thoroughly in a skillet breaking it into small pieces and draining any excess fat. Grate the mozzarella cheese and chop any extra toppings you are adding now is the time to get everything prepped for layering.
Top and Finish Baking:
Once the biscuits are partially baked remove from the oven. Top evenly with pizza sauce then the cooked sausage mozzarella cheese and pepperoni slices. Add any other toppings you like. Return the dish to the oven and bake for another ten to fifteen minutes until the cheese is fully melted and bubbly and the pepperoni looks crisp at the edges.
Serve and Enjoy:
Let it cool for five to ten minutes so it sets slightly before slicing in. The cheesy biscuit layers will be gooey and golden ready to serve hot.
A baked pizza with pepperoni and cheese.
A baked pizza with pepperoni and cheese. | lilicooks.com

My favorite part of this dish is always that garlic butter soaked biscuit layer. When I was young my siblings and I used to fight over the corner pieces because they got just a little extra crispy and cheesy. Making this casserole now always brings back memories of those noisy laughter filled dinners.

Storage Tips

Bubble Up Pizza Bake stores beautifully in the fridge for up to three days. Make sure to let it cool completely before covering tightly with foil or transferring to an airtight container. For best results reheat portions in the oven at 350 degrees until bubbly and warm which keeps the biscuits from getting soggy. Avoid microwaving as it can make the biscuit pieces chewy.

Ingredient Substitutions

No Italian sausage on hand ground turkey or beef works just as well for a milder flavor. You can swap out mozzarella for provolone or cheddar if desired and even use homemade biscuit dough if you want more control over ingredients. Feel free to skip the pepperoni or add cooked vegetables like mushrooms or bell peppers based on your family’s favorites.

A slice of pizza with pepperoni and cheese on a white plate.
A slice of pizza with pepperoni and cheese on a white plate. | lilicooks.com

Serving Suggestions

Serve with a simple green salad dressed with a tangy vinaigrette to balance the richness of the casserole. For a party spread cut into smaller squares and serve as finger food paired with ranch or marinara for dipping. This recipe is also a hit at potlucks and game days just keep it warm in a low oven until ready to serve.

Cultural and Historical Context

This pizza bake is a classic example of American comfort food ingenuity using convenience ingredients to recreate favorite flavors in a family friendly format. Bubble up casseroles became popular in the Midwest as a way to stretch ingredients and make dinnertime fun without much fuss. The method has roots in potluck culture where hearty casseroles are a staple.

Recipe FAQs

→ Can I use a different type of biscuit?

Yes, you can use any brand or style of refrigerated biscuits you like for this dish.

→ What other toppings work well?

Try mushrooms, bell peppers, red onions, olives, or cooked bacon for extra variety.

→ Can this be prepared ahead of time?

You can assemble the biscuit base in advance, but add the sauce and toppings just before baking for best texture.

→ Is it freezer-friendly?

It's best enjoyed fresh, but you can freeze leftovers. Reheat thoroughly before serving.

→ What sides go well with this meal?

A crisp green salad or roasted vegetables pair nicely with the cheesy, hearty bake.

Bubble Up Pizza Bake

Cheesy, savory pizza casserole featuring biscuits, sausage, and pepperoni; perfect for sharing.

Preparation Time
10 min
Cooking Time
25 min
Overall Time
35 min
Created By: Lili Clark

Category: Grandma's Legacy

Skill Level: Beginner-Friendly

Cuisine Type: American

Output: 6 Serves

Dietary Options: ~

Ingredients

→ Base Ingredients

01 1 16.3 oz can of Pillsbury Homestyle Biscuits or any brand and type of biscuits

→ Butter and Seasoning

02 4 tablespoons salted butter, melted
03 5-6 garlic cloves, minced
04 1 tablespoon dried oregano or Italian seasoning
05 1 teaspoon dried parsley
06 1/2 cup grated Parmesan cheese

→ Toppings

07 14 oz pizza sauce
08 1 lb Italian sausage, browned
09 16 oz grated mozzarella cheese
10 6 oz pepperoni slices
11 Any additional pizza toppings of your choice

Steps

Step 01

Preheat the oven to 400°F (200°C).

Step 02

Cut each biscuit into 9 equal-sized pieces and set aside.

Step 03

In a bowl, melt the butter, then add the oregano, parsley, minced garlic, and Parmesan cheese. Toss the biscuit pieces into the mixture.

Step 04

Layer the coated biscuit pieces into a 9x13-inch baking dish. Bake for 12-15 minutes until the biscuits are cooked through.

Step 05

While the biscuits are baking, brown the Italian sausage, grate the cheese, and prepare any additional toppings.

Step 06

Remove the biscuits from the oven. Top them with pizza sauce, browned sausage, grated mozzarella, pepperoni slices, and any additional toppings.

Step 07

Return the dish to the oven and bake for an additional 10-15 minutes, or until the cheese is melted and the pepperoni is crispy.

Step 08

Serve hot and enjoy your Bubble Up Pizza Bake.

Tips

  1. You can add any variety of toppings to customize the pizza bake to your taste.

Required Tools

  • Oven
  • 9x13-inch baking dish
  • Mixing bowl
  • Knife and cutting board
  • Sauté pan

Allergy Information

Always check each ingredient for allergens, and consult a medical professional if unsure.
  • Contains dairy (butter, Parmesan cheese, mozzarella cheese)
  • Contains gluten (biscuits)
  • Contains meat (Italian sausage, pepperoni)

Nutritional Information (per serving)

These details are shared for general guidance and don’t replace professional advice.
  • Calories: 560
  • Fats: 32 g
  • Carbohydrates: 42 g
  • Proteins: 24 g